Most of our studies are based on optical spectroscopic techniques, mainly UV-Vis absorption and fluorescence. Other techniques, such as Rayleigh light scattering and atomic force microscopy (AFM) and recently Isothermal Calorimetry (ITC) are also used. We work in close collaboration with other groups, which cover a plethora of different techniques and approaches, from in vitro to in vivo studies.

The following methodologies were conceived and/or developed in our lab:

Information aimed	Experimental approach
Partition coefficient	Fluorescence decays, anisotropy and Zeta -Potential
In-depth distribution profile	Fluorescence quenching
Molecular orientation	UV-Vis, Linear dichroism
Self association	Energy transfer, ITC
Inter-domain distribution	Fluorescence quenching (transient state)
Spectral correction for turbidity	UV-Vis. absorption.